We run a full DNA profile on all of our adult dogs to ensure we are taking all the necessary steps to not only be responsible but to do our part to better the breed.
All of our adults of age have had hip & elbow testing and have received a certified OFA record from the Orthopedic Foundation for Animals.
All of our adults are cleared by parentage for all eye deformalities.
All eye diseases can be ruled out with DNA testing, but we will do a CERF test, if there is anything in question.
Stands for Orthopedic Foundation for Animals
Tests for hip and elbow displacia
includes a set of x-rays sent in to the OFA where they are reviewed by a panel of 3 veteranarians.
Hips are graded: POOR, GOOD or EXCELLENT
Elbows are graded: NORMAL or ABNORMAL
Includes a sample of saliva sent to a lab. Lab results varify if dog is a
*CARRIER - has one copy of the gene
*AFFECTED - has two copies of the gene
or *CLEAR - no gene present
test includes MDR-1, CEA, CD, DM, HC, HUU, MR-1, NCL, PRA/PRCD and are explained below.
Canine Eye Registration Foundation
includes an eye screening by a board certified vet. The eye is dialated and examined with a pen light to detect any abnormalities. Tests should be conducted yearly. But, will only show problems after they have occurred. DNA testing is the best way to know if there are any eye deformities to be aware of.
Multi Drug Resistance gene
Dogs with two copies of the mutated gene will develop a sensitivity to ivermectin and similar drugs. Dogs with the mutation will pass on one copy of the gene to their puppies.
Drugs sensitive to MDR-1
affected dogs include:
*Ivermectin (found in heartworm medications)
(Imodium over the counter antidiarrheal agent)
*Doxorubicin, Vincristine, Vinblastine
*Cyclosporin (immunosuppressive agent)
*Digoxin (heart drug)
*Butorphanol ("Bute" pain control)
Collie Eye Anamoly
The disorder causes abnormal development in layers of tissue in the eye under the retina called the choroid.
These changes cause what is referred to as Choroidal Hypoplasia. The abnormal choroid appears pale and translucent. In most cases CEA is present at birth and can be detected in puppies as young as 4-8 weeks of age. There is currently no treatment for this disease.
Cone Degeneration disease causes day-blindness caused by a lack of cone function in the retina of the eye.
is a progressive neurological disorder that affects the spinal cord of dogs.
Dogs that have inherited two defective copies will experience a breakdown of the cells responsible for sending and receiving signals from the brain, resulting in neurological symptoms.
clouding of the lens of the eye caused by a breakdown of tissue in the eye. This condition generally results in an inability to see clearly and can cause total blindness. In canines, cataracts are often familial; this type is known as Hereditary Cataracts.
Dogs with this genetic mutation metabolize waste products as uric acid in their urine
The uric acid forms into hard stones in the bladder, causing pain and inflammation as the stone moves through the urinary tract.
autosomal recessive genetic ocular disease characterized by retinal deformation
Neuronal Ceroid Lipofuscinosis
result in progressive degeneration of the central nervous system.
Characteristic neurological signs of NCL include mental dullness, Ataxia, loss of vision, weakness, abnormal gait, seizures, tremors and aggressive behaviors.
Progressive Retinal Atrophy
Progressive Rod Cone Degeneration
PRA - disorder in which the cells in the retina of a dog degenerate and die, in most cases eventually leading to complete blindness
PRCD - degeneration of both rod and cone type Photoreceptor Cells of the Retina, which are important for vision in dim and bright light, respectively.